Selected Publications

Liston A. Autoimmunity: Beyond the immune system. Immunol Cell Biol. 2008; 1-2. Abstract

Lonyai A, Kodama S, Burger D, Faustman DL. Fetal Hox11 expression patterns
predict defective target organs: a novel link between developmental biology
and autoimmunity. Immunol Cell Biol. 2008; 1-9. Abstract

Lonyai A, Kodama S, Burger D, Davis M, Faustman DL. The promise of Hox11+ stem cells of the spleen for treating autoimmune diseases. Horm Metab Res. 2008; 40:137-46. Abstract

Tran SD, Kodama S, Lodde BM, Szalayova I, Key S, Khalili S, Faustman DL,
Mezey E. Reversal of Sjogren’s-like syndrome in non-obese diabetic mice.
Ann Rheum Dis. 2007; 66:812-4. Abstract

Dieguez-Acuna FJ, Gygi SP, Davis M, Faustman DL. Splenectomy: a new
treatment option for ALL tumors expressing Hox-11 and a means to test the
stem cell hypothesis of cancer in humans. Leukemia. 2007; 21;2192-235. Abstract

Faustman DL. Reversal of type 1 diabetes in mice. N Engl J Med. 2007;
356:311-2. Abstract

Faustman DL. Permanent reversal of diabetes in NOD mice. Science. 2007;
317:196. Abstract

Dale E, Davis M, Faustman DL. A role for transcription factor NF-kB in
autoimmunity: possible interactions of genes, sex, and the immune response.
Adv Physiol Edu. 2006; 30:152-8. Abstract

Kodama S, Davis M, Faustman DL. Regenerative medicine: a radical
reappraisal of the spleen. Trends Molec Med. 2005; 11:271-6. Abstract

Kodama S, Davis M, Faustman DL. Diabetes and Stem Cell Researchers Turn to
the Lowly Spleen. Sci Aging Knowl. Environ. 2005; pe2. Abstract

Dieguez-Acuna FJ, Gerber SA, Kodama S, Elias JE, Beausoleil SA, Faustman D,
Gygi SP. Characterization of mouse spleen cells by subtractive proteomics.
Molec Cell Proteomics. 2005: 4:1459-70. Abstract

Kuhtreiber WM, Kodama S, Burger DE, Dale EA, Faustman DL. Methods to
characterize lymphoid apoptosis in a murine model of autoreactivity. J
Immunol Meth. 2005; 306:137-50. Abstract

Kodama S, Davis M, Faustman DL. The therapeutic potential of tumor necrosis
factor for autoimmune disease: a mechanistically based hypothesis. Cell
Molec Life Sci. 2005; 62: 1850-62. Abstract

Kodama S, Faustman DL. Routes to regenerating islet cells: stem cells and
other biological therapies for type 1 diabetes. Pediatric Diabetes. 2004;
5:38-44. Abstract

Kuhtreiber WM, Kodama S, Burger DE, Dale EA, Faustman DL. Methods to characterize lymphoid apoptosis in a murine model of autoreactivity. J Immunol Methods. 2005 Nov 30;306(1-2):137-50. Abstract

Dieguez-Acuna FJ, Gerber SA, Kodama S, Elias JE, Beausoleil SA, Faustman D, Gygi SP. Characterization of mouse spleen cells by subtractive proteomics. Mol Cell Proteomics. 2005 Oct;4(10):1459-1470. Abstract

Kodama S, Davis M, Faustman DL. The therapeutic potential of tumor necrosis factor for autoimmune disease: a mechanistically based hypothesis. Cell Mol Life Sci. 2005 Aug;62(16):1850-62. Abstract

Kodama S, Davis M, Faustman DL. Regenerative medicine: a radical reappraisal of the spleen. Trends Mol Med. 2005 Jun;11(6):271-6. Abstract

Kodama S, Davis M, Faustman DL. Diabetes and stem cell researchers turn to the lowly spleen. Sci Aging Knowledge Environ. 2005 Jan 19;2005(3):pe2. Abstract

Kodama S, Faustman DL. Routes to regenerating islet cells: stem cells and other biological therapies for type 1 diabetes. Pediatr Diabetes. 2004;5 Suppl 2:38-44. Abstract

Abraham EJ, Kodama S, Lin JC, Ubeda M, Faustman DL, Habener JF. Human pancreatic islet-derived progenitor cell engraftment in immunocompetent mice. Am J Pathol. 2004 Mar;164(3):817-30. Abstract

Kuhtreiber WM, Hayashi T, Dale EA, Faustman DL. Central role of defective apoptosis in autoimmunity. J Mol Endocrinol. 2003 Dec;31(3):373-99. Abstract

Hayashi T, Faustman DL. Role of defective apoptosis in type 1 diabetes and other autoimmune diseases. Recent Prog Horm Res. 2003;58:131-53. Abstract

Penfornis A, Yan G, Shi L, Faustman DL. Polymorphisms of human TAP2 detected by denaturing gradient gel electrophoresis. Hum Immunol. 2003 Jan;64(1):156-67. Abstract

Yan G, Shi L, Penfornis A, Faustman DL. Impaired processing and presentation by MHC class II proteins in human diabetic cells. J Immunol. 2003;170:620-7. Abstract

Kodama S, Kuhtreiber W, Fujimura S, Dale EA, Faustman DL. Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science. 2003;302:1223-7. Abstract

Hayashi T, Faustman DL. Development of spontaneous uterine tumors in low molecular mass polypeptide-2 knockout mice. Cancer Res. 2002 Jan 1;62(1):24-7. Abstract

Hayashi T, Faustman DL. Selected contribution: Association of gender-related LMP2 inactivation with autoimmune pathogenesis. J Appl Physiol. 2001 Dec;91(6):2804-15. Abstract

Ryu S, Kodama S, Ryu K, Schoenfeld DA, Faustman DL. Reversal of established autoimmune diabetes by restoration of endogenous ß-cell function. J Clin Invest. 2001; 108:63-72. Abstract

Hayashi T, Faustman DL. Implications of altered apoptosis in diabetes mellitus and autoimmune disease. Apoptosis. 2001 Feb-Apr;6(1-2):31-45. Abstract

Hayashi T, Faustman D. Essential role of human leukocyte antigen-encoded proteasome subunits in NF-kappaB activation and prevention of tumor necrosis factor-alpha-induced apoptosis. J Biol Chem. 2000 Feb 18; 275(7):5238-47. Abstract

Hayashi T, Kodama S, Faustman D. Reply to 'LMP2 expression proteasome activity in NOD mice. Nature Med. 2000; 6:1065-66. Abstract

Hayashi T, Faustman D. Defective function of the proteasome in autoimmunity: involvement of impaired NF-kappaB activation. Diabetes Technol Ther. 2000 Autumn;2(3):415-28. Abstract

Hayashi T, Faustman D. NOD mice are defective in proteasome production and activation of NF-kappaB. Mol Cell Biol. 1999 Dec; 19(12):8646-59. Abstract

Yan G, Shi L, Fu Y, Wang X, Schoenfeld D, Ma L, Penfornis A, Gebel H, Faustman DL. Screening of the TAP1 gene by denaturing gradient gel electrophoresis in insulin-dependent diabetes mellitus: detection and comparison of new polymorphisms between patients and controls. Tissue Antigens. 1997 Dec;50(6):576-85. Abstract

Faustman DL. Gender is important: lessons in autoimmunity. J Womens Health. 1997 Oct;6(5):521-2. Abstract

Yan G, Fu Y, Faustman DL. Reduced expression of Tap1 and Lmp2 antigen-processing genes in the nonobese diabetic (NOD) mouse due to a mutation in their shared bidirectional promoter. J Immunol. 1997 Sep 15;159(6):3068-80. Abstract

Huang R, Guo J, Li X, Faustman DL. Elimination of self-peptide major histocompatibility complex class I reactivity in NOD and beta 2-microglobulin-negative mice. Diabetes. 1995 Sep;44(9):1114-20. Abstract

Li F, Linan MJ, Stein MC, Faustman DL. Reduced expression of peptide-loaded HLA class I molecules on multiple sclerosis lymphocytes. Ann Neurol. 1995 Aug;38(2):147-54. Abstract

Wang F, Li X, Annis B, Faustman DL. Tap-1 and Tap-2 gene therapy selectively restores conformationally dependent HLA Class I expression in type I diabetic cells. Hum Gene Ther. 1995 Aug;6(8):1005-17. Abstract

Faustman DL. Altered MHC class I expression: a role for transplantation and IDDM autoimmunity. Diabetes Metab Rev. 1995 Apr;11(1):1-19. Abstract

Vidal-Puig A, Faustman DL. Tolerance to peripheral tissue is transient and maintained by tissue-specific class I expression. Transplant Proc. 1994 Dec;26(6):3314-6. Abstract

Li F, Guo J, Fu Y, Yan G, Faustman D. Abnormal class I assembly and peptide presentation in the nonobese diabetic mouse. Proc Natl Acad Sci USA. 1994;91:11128-32. Abstract

Faustman DL. Occult CD45 T cell developmental defect in type 1 diabetes. Diabete Metab. 1993 Sep-Oct;19(5):446-57. Abstract

Li X, Golden J, Faustman DL. Faulty major histocompatibility complex class II I-E expression is associated with autoimmunity in diverse strains of mice. Autoantibodies, insulitis, and sialadenitis. Diabetes. 1993 Aug;42(8):1166-72. Abstract

Fu Y, Nathan DM, Li F, Li X, Faustman DL. Defective major histocompatibility complex class I expression on lymphoid cells in autoimmunity. J Clin Invest. 1993;91:2301-7. Abstract

Faustman DL. MHC class I and autoimmune diabetes. Biomed Pharmacother. 1993;47(1):3-10. Abstract

Lanza RP, Butler DH, Borland KM, Harvey JM, Faustman DL, Solomon BA, Muller TE, Rupp RG, Maki T, Monaco AP, et al. Successful xenotransplantation of a diffusion-based biohybrid artificial pancreas: a study using canine, bovine, and porcine islets. Transplant Proc. 1992 Apr;24(2):669-71. Abstract

Faustman D, Coe C. Prevention of xenograft rejection by masking donor HLA class I antigens. Science. 1991 Jun;252(5013):1700-2. Abstract

Faustman D, Li XP, Lin HY, Fu YE, Eisenbarth G, Avruch J, Guo J. Linkage of faulty major histocompatibility complex class I to autoimmune diabetes. Science. 1991 Dec 20;254(5039):1756-61. Abstract

Lanza RP, Butler DH, Borland KM, Staruk JE, Faustman DL, Solomon BA, Muller TE, Rupp RG, Maki T, Monaco AP, et al. Xenotransplantation of canine, bovine, and porcine islets in diabetic rats without immunosuppression. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11100-4. Abstract

Breitmeyer JB, Faustman DL. Sheep erythrocyte rosetting induces multiple alterations in T lymphocyte function: inhibition of T cell receptor activity and stimulation of T11/CD2. Cell Immunol. 1989 Oct 1;123(1):118-33. Abstract

Faustman DL, Hauptfeld V, Davie JM, Lacy PE. Prolonged survival of donor skin grafts on mice bearing established islet of Langerhans transplants. Transplantation. 1985 Aug;40(2):216-8. Abstract

Faustman DL, Steinman RM, Gebel HM, Hauptfeld V, Davie JM, Lacy PE. Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody. Proc Natl Acad Sci U S A. 1984 Jun;81(12):3864-8. Abstract

 

 

All material copyright 2006

Home | Research | News & Updates | Publications | FAQs | Related Links | Contact | Support